Weekly treatment with Context Therapeutics’ CTIM-76 was generally well tolerated and shrank tumors in some people with heavily pretreated platinum-resistant ovarian cancer, according…
Gynecological cancer
GYNECOLOGICAL CANCER
Cellxlife gains license to ovarian cancer vaccine in clinical trials
Cellxlife signed a licensing agreement for a cell-based vaccine from Mayo Clinic that aims to teach the body’s immune system to recognize and…
GYNECOLOGICAL CANCER
Experimental drug shrinks tumors in hard-to-treat cancers
SIM0505, a treatment being developed by Nextcure and Simcere Zaiming, resulted in partial responses in more than half of patients with hard- to-treat…
GYNECOLOGICAL CANCER
Immunotherapy duo shows promise in tough gynecological cancers
A combination of the immune-modulating treatments Lymphir (denileukin diftitox) and Keytruda (pembrolizumab) led to clinical benefit in nearly half of evaluable patients in an exploratory clinical…
GYNECOLOGICAL CANCER
Vaccine plus Keytruda bests standard care for hard-to-treat ovarian cancer
The experimental cancer vaccine Tedopi (OSE2101), when given in combination with the approved injection therapy Keytruda (pembrolizumab), outperforms standard-of-care treatment in delaying disease…
GYNECOLOGICAL CANCER
New therapy bests chemo at improving survival in endometrial cancer
A large clinical trial testing Merck’s therapy candidate sacituzumab tirumotecan (sac-TMT) in people with hard-to-treat endometrial cancer has achieved its main goal, with sac-TMT…
GYNECOLOGICAL CANCER
Lira-cel well tolerated so far in early recurrent ovarian cancer trial
Liraltagene autoleucel (lira-cel), an experimental cell therapy in clinical development for recurrent ovarian cancer, has been tolerated well so far in an early clinical trial,…
GYNECOLOGICAL CANCER
World Ovarian Cancer Day campaign spotlights scars seen and unseen
May 8 is World Ovarian Cancer Day, a time when advocates around the world raise their voices to increase awareness, support those affected, and…
GYNECOLOGICAL CANCER
FDA gives fast track edge to ovarian cancer combo therapy now in testing
The U.S. Food and Drug Administration (FDA) has granted fast track status to a combination of lunresertib and zedoresertib — two therapies in development by…
GYNECOLOGICAL CANCER
Mo-Rez shows strong early responses in ovarian, endometrial cancers
In an early clinical trial, people with certain advanced or treatment-resistant gynecological cancers showed strong responses to the experimental therapy mocertatug rezetecan (Mo-Rez), according…
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