Researchers Develop New Animal Model of Multiple Myeloma
Researchers in the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed a new animal model of multiple myeloma,…
News
Potential Therapeutic Target for Drug-resistant Multiple Myelomas Identified in Study
A subunit of a signaling protein may be a new therapeutic target in multiple myeloma (MM), a hematologic malignancy with high relapse rates and resulting drug resistance in patients, according…
New Adjuvant Therapy Shows Promising Results to Treat Multiple Myeloma, B-Cell Malignancies
A new class of drugs that activate a protein in cells’ endoplasmic reticulum may be used as an adjuvant therapy to treat B-cell malignancies, according to the…
Disrupting Specific Protein May Be Effective Multiple Myeloma Treatment Strategy
Researchers at Buffalo, New York-based Roswell Park Cancer Institute revealed that knocking down individual RabGTPases (Rab) proteins in myeloma cells was sufficient to disrupt the trafficking of…
Protein Identified that May Point to Myeloma Patients Likely to Respond to Proteasome Inhibitors
Researchers at The University of Texas MD Anderson Cancer Center, in collaboration with other institutions, identified a gene called TJP1 that could help predict which…
Takeda Publishes Promising Trial Results on Ixazomib, an Approved Drug to Treat Relapsed Multiple Myeloma
Takeda Pharmaceutical has published promising data from the TOURMALINE-MM1 Phase 3 clinical trial of patients with relapsed and/or refractory multiple myeloma (MM), treated with the combination…
International Myeloma Foundation Funds First Broad Screening of Disease at Earliest Stage
The International Myeloma Foundation (IMF) has announced new funding for the first comprehensive screening study that aims to prevent myeloma before it develops. The funded study, titled “iStopMM (Iceland…
Multiple Myeloma Cancer Stem Cells Decreased with Novel Antibody Medi-551
A preliminary clinical study at Johns Hopkins Kimmel Cancer Center demonstrated that antibody treatment could decrease by half the number of cancer stem cells, which…
Study Explores Challenges of Treating Myeloma in the Elderly
The diagnosis and management of myeloma in the very elderly is especially challenging, despite improvements in therapies. A review study, “Multiple myeloma in the very…
MedImmune’s Antibody Therapy Seen to Effectively Reduce Cancer Stem Cells in Most Newly Diagnosed Multiple Myeloma Patients
A research team led by William Matsui, MD, and Carol Ann Huff, MD, with the Johns Hopkins Kimmel Cancer Center, has found that MedImmune’s novel MEDI-551 antibody treatment…
