Extra Weight in Precancerous Stages Increases Risk of Multiple Myeloma, Study Finds
Patients in a precancerous stage of multiple myeloma would be wise to avoid gaining extra weight, according to new research that shows being overweight or obese…
Myeloma
Ninlaro Granted Conditional Approval by European Commission to Treat Multiple Myeloma
The European Commission has granted conditional marketing authorization to Ninlaro (ixazomib) capsules in combination with Revlimid (lenalidomide) and Decadron (dexamethasone) for multiple myeloma patients who…
Nonspecific Symptoms Including Back Pain Should Be Red Flags for Myeloma, Study Suggests
A combination of nonspecific symptoms, including back pain and weight loss, should alert physicians to the possibility of multiple myeloma. Still, the recognition of symptom patterns…
FDA OKs Darzalex as Combination Therapy for Relapsed or Refractory Myeloma Patients
The U.S. Food and Drug Administration (FDA) has approved Darzalex (daratumumab), in combination with Revlimid (lenalidomide) and dexamethasone, or Velcade (bortezomib) and dexamethasone, for multiple…
Drug Therapy Combo May Have Led to Toxic Epidermal Necrolysis in Multiple Myeloma Patient
Multiple myeloma patients taking the immunomodulatory drug thalidomide may develop a potentially life-threatening dermatologic disorder called toxic epidermal necrolysis (TEN), according to a recent case…
Oral 3-Drug Combo Looks Promising in Treatment-Resistant Myeloma
Combining three well-known oral drugs shows potential for heavily pretreated multiple myeloma patients who have grown resistant to therapy with one of the included drugs, according…
Kyprolis Combo Seen to Improve Life Quality in Relapsed Multiple Myeloma Patients
Adding the proteasome inhibitor Kyprolis (carfilzomib) to the standard two-drug regimen of Revlimid (lenalidomide) and dexamethasone significantly improves health-related quality of life in relapsed multiple…
Phase 3 Trial Will Assess Darzalex-containing Combo Therapy in Multiple Myeloma Patients
The anti-CD38 agent Darzalex (daratumumab) will be investigated in a Phase 3 clinical trial in combination with Kyprolis (carfilzomib) and Decadron (dexamethasone) in relapsed/refractory multiple…
FDA Places Hold on BioInvent’s Phase 2 Trial for Multiple Myeloma Therapy
The U.S. Food and Drug Administration (FDA) has verbally notified BioInvent International that it’s placing a full clinical hold on the company’s Phase 2 trial evaluating…
Karyopharm to Present Updated Clinical Data of Selinexor in Multiple Myeloma Patients
Karyopharm Therapeutics is set to present novel clinical data on its lead product candidate selinexor, an oral selective inhibitor of nuclear export compound that…
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